Administer loading dose regardless of previous clopidogrel use1
Begin maintenance dose 12 hours after loading dose2
Tablet images are not actual size.
BRILINTA can be administered with or without food1
A patient who misses a dose of BRILINTA should take one 90-mg tablet (the next dose) at its scheduled time1
BRILINTA is metabolized by the liver and impaired hepatic function can increase risks for bleeding and other adverse events. No dosage adjustment is needed in patients with mild hepatic impairment. BRILINTA has not been studied in moderate to severe hepatic impairment. For patients with moderate hepatic impairment, consider the risks and benefits of treatment and carefully consider use. For patients with severe hepatic impairment, BRILINTA is contraindicated1
No dosage adjustment is needed in patients with renal impairment. Patients on dialysis have not been studied1
BRILINTA is metabolized by CYP3A4/5. Avoid use with strong CYP3A inhibitors and potent CYP3A inducers. Avoid simvastatin and lovastatin doses >40 mg. Monitor digoxin levels with initiation of, or any change in, BRILINTA therapy
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.